Sanchez was married to Florida Galeai'i, and together they have had children: Simon II, Anthony Peter, Antolina S. Leon Guerrero, Florida, Dolores Anne, Paul, and Amanda.
Ricardo J. Bordallo ran with Sanchez as his running mate in the 1978 election for Governor of Guam.
The Bordallo-Sanchez ticket was defeated in the general election by the Republican Calvo-Ada team.
In 1986, Sanchez ran as a Democrat for a seat in the Guam Legislature.
A special election was held in November 1987 to fill the vacant seat left by Sanchez' death.