Pendergrass is a city in Jackson County, Georgia, United States.

[7] It is bordered to the southeast by Jefferson, the county seat, and to the northwest by Talmo.

U.S. Route 129 passes through the northeast side of the city, leading northwest 14 miles (23 km) to Gainesville and southeast through Jefferson 24 miles (39 km) to Athens.

There were 171 housing units at an average density of 84.4 per square mile (32.6/km2).

17.9% of all households were made up of individuals, and 8.3% had someone living alone who was 65 years of age or older.