Penncrest High School is a public four-year comprehensive high school in Middletown Township, Delaware County, Pennsylvania, United States in the Philadelphia metropolitan area.

The majority, around 78.7%, of the school district identified as White, with 21.2% of students being minorities.

Penncrest competed in 12 interscholastic boys' sports and 11 girls' sports including boys' baseball, basketball, cross country running, American football, golf, indoor and outdoor track and field, lacrosse, soccer, swimming and diving, tennis, and wrestling.

Girls competed in basketball, cross country running, field hockey, indoor and outdoor track and field, lacrosse, softball, soccer, swimming and diving, tennis, and volleyball.

Penncrest competes in the Central League, District One, of the Pennsylvania Interscholastic Athletic Association (PIAA).