In 1903, the district was drawn to cover Crawford and Erie counties, which had been its original area 60 years earlier.
The district was again moved in 1922, when it was redrawn to cover Washington and Greene counties.
Greene County was transferred to the 24th District while parts of Allegheny County south and west of down-town Pittsburgh were moved to the 25th District.
These boundaries were then redrawn in 1972, with a small strip of northern Allegheny County being put in the 25th district.
The district was eliminated as a result of the redistricting cycle after the 1980 census.