The road continues northwest through more wooded areas to the northeast of the CSX line and the Monongahela River, passing by the Charleroi Locks & Dam.
At this point, the route widens into a four-lane divided highway and turns north, crossing into the city of Monessen and heading past commercial establishments as it intersects the eastern approach to the Charleroi-Monessen Bridge.
The two directions of PA 906 rejoin and head east on four-lane divided Schoonmaker Avenue, passing between commercial and industrial areas to the north and woods to the south.
PA 906 becomes an unnamed road and heads through more wooded areas at the bottom of a cliff with the CSX line and the Monongahela River paralleling it to the northwest.
The one-way pair runs through more of the community before both directions of PA 906 rejoin and follow two-lane undivided North Road.