Peptoid nanosheet

Peptoid nanosheets have a thickness of about three nanometers and a length of up to 100 micrometers, meaning that they have a two-dimensional, flat shape that resembles paper on the nanoscale.

[1] This makes them one of the thinnest known two-dimensional organic crystalline materials with an area to thickness ratio of greater than 109 nm.

For assembly, a purified amphiphilic polypeptoid of specific sequence is dissolved in aqueous solution.

When this mono-layer is shrunk, it buckles into a bilayer with the hydrophobic groups forming the interior core of the peptoid nanosheet.

Peptoid nanosheets have a very high surface area, which can be readily functionalized to serve as a platform for sensing and templating.