Percy Walker (1812–1880) was an American politician from Huntsville, Alabama.
He was graduated from the medical department of the University of Pennsylvania at Philadelphia in 1835.
He began practicing medicine in Mobile, Alabama.
He was elected to the State House of Representatives in 1839, 1847, and 1853, elected as a candidate of the American Party to the Thirty-fourth Congress (4 March 1855 – 3 March 1857).
He died in Mobile on 31 December 1880, and was interred in Magnolia Cemetery.