In case of neurons, the soma receives a large number of inhibitory synapses,[6] which can regulate the activity of these cells.
It has also been shown that microglial processes constantly monitor neuronal functions through somatic junctions, and exert neuroprotection when needed.
A high amount of protein synthesis occurs in this region, as it contains many Nissl granules (which are ribosomes wrapped in RER) and polyribosomes.
In addition, the axon hillock also has a specialized plasma membrane that contains large numbers of voltage-gated ion channels, since this is most often the site of action potential initiation and triggering.
The neurofilaments become cross linked with certain fixatives and when impregnated with silver, they form neuro fibrils visible with the light microscope.