Pernell is an unincorporated community in Garvin County, Oklahoma, United States.

Pernell is located on Oklahoma State Highway 76, 8 miles (13 km) southwest of Elmore City.

Pernell had a post office, which opened on June 28, 1922 and closed on December 27, 2003.

[2] After the post office closed, Pernell addresses were incorporated with Elmore City.

The community was named after resident Thomas Pernell.