It is primarily engaged in cloud computing, internet of things, endpoint security, big data analytics and software product engineering services.

[8] In 2015, Persistent Systems completed the acquisition of the digital content management solutions business of US-based Akumina.

[13] In 2019, Persistent joined Siemens' MindSphere partner program to deliver industrial internet of things (IIoT) services.

[22] On Sept 30, 2024, Persistent Systems declared its intention to acquire Arrka, a Pune-based data privacy management firm for a consideration of Rs 14.4 crore.

[24] The company also organizes IBM's Call for Code hackathon at its Goa, Nagpur and Pune offices.