[2] They decided to call "for a halt to the indiscriminate sale and misuse of hazardous chemical pesticides throughout the world"[2] and proposed a model that would be based on an international communication network with regional nodes.

[7] PAN lobbied international institutions to regulate pesticide trade by drawing on the concept of "prior informed consent".

[8] PAN led a civil society campaign that gained the support of the chemical industry in the early 1990s, after their initial opposition.

On 5 June 1985 it launched the international “Dirty Dozen” campaign, with actions that included protests at plants manufacturing chemicals on the list such as the Dow plant in New Zealand that produced the herbicide 2,4,5-T.[7] In 1987, it called for the insecticide chlordimeform to be removed from the US market due to being a potential human carcinogen.

[18] In 2000, Genetically Engineered Food Alert was launched by multiple organizations, including Pesticide Action Network North America, to lobby the FDA, Congress and companies to ban or stop using GMOs.