He was a nephew is Metropolitan Nathanael of Ohrid, who lead him to Plovdiv, Eastern Rumelia, where he studied at a high school.
Sentenced in March 1899 to a life prison for a conspiracy, Mandzhukov appealed the verdict, and in the same year the court dismissed him for failing to prosecute.
In 1900 together with Pavel Shatev, Slavi Merdjanov and Petar Sokolov he took part in the terrorist activity around the Ottoman Bank in Istanbul.
[3] In September 1901, he was head of a small detachment, and attempted to free his friend Slavi Merdzhanov from the Adrianople prison, but failed.
With the new detachment, he attempted to destroy the railway line near Xanthi to prevent the transfer of Ottoman troops to Thessaloniki.
Mandzhukov then reconsidered his role in this organization, alien to his anarchist views and cut his ties with Supreme Committee.