He began his main research interests at the Massachusetts General Hospital and Harvard Medical School.
[4][5] Butler began the experimental work leading towards facial transplantation in 1993 at the Massachusetts General Hospital and Harvard Medical School.
[10][11] However, Butler stated in a 27 October press release that their team "will not be rushed" and "It may be some time before we are ready to carry out an operation.
[12] Butler began his research in tissue engineering in 1993 at the Massachusetts General Hospital and Harvard Medical School with Charles Vacanti, Jay Vacant and Robert Langer.
He has the biggest worldwide treatment numbers for oro-facial fibrosis secondary to scleroderma and other rare diseases.
Further innovation in the treatment of lichen sclerosus has been awarded prizes by the British Society for the Study of Vulval Diseases.
[14] This work is carried out as part of the newly formed Charles Wolfson Centre of Reconstructive Surgery.