Peter Christian Knudtzon (19 March 1789–17 November 1864) was a Danish businessman and ship-owner.

He was the father of Governor of the Bank of Denmark Søren Christian Knudtzon [da].

He engaged in a number of speculative investments, especially on the property market in Copenhagen, with considerable success.

In 1834 he founded Icelands first and Oldest Bakery Bernhöftsbakari In 1855, P. C. Knudtzon & Søn's fleet consisted of the brigs Wilhelmine and Johanne, the schooners Harriet, Louise, Lucinde and Marie, the galleass Emmy, and the yachts Anna Helena, Cathinca, Christiansgave, Kis and Orøven.

In 1831, he was instrumental in establishing the Grossist Society's relief fund (Danish: understøttelsesfond), together with his friend Christian Rønnenkamp and the firm Hambro & Søn.

Following the death of his first wife on 13 November 1839, Knudtzon married Lucinde Gotschalk (17 March 1818–17 December 1888) in St. Peter's Church in Copenhagen.