Devreotes started his independent career as an assistant professor at the department of biological chemistry]in the Johns Hopkins University School of Medicine in 1980.
[14] Devreotes trained more than 75 doctoral students and post-doctoral fellows, many of whom have received senior and distinguished positions in major research institutes (such as University of Michigan, Perelman School of Medicine, Johns Hopkins University, Beatson institute, UTSW, Weill Cornell Medicine, NIAID ) and in different industry.
[7][22] Subsequent research in Devreotes lab helped to uncover the GPCR kinetics and phosphoinositides biology of the polarity organization in migrating Dictyostelium and leukocyte cells.
[23][24] Inside the scientific community, he is widely credited for bringing system-level understanding and implementing computational analysis of dynamical systems in different cell physiological processes.
focus on the understanding the dynamics of internal feedback loops in signal transduction and cytoskeletal networks that confer the biochemical excitability to the membrane and thus control different morphological and functional properties of the cell.