The Petitcodiac River campaign was a series of British military operations from June to November 1758, during the French and Indian War (the North American theatre of the Seven Years' War), to deport the Acadians that either lived along the Petitcodiac River or had taken refuge there from earlier deportation operations, such as the Ile Saint-Jean campaign.

Many Acadians fled those operations to present-day New Brunswick and the French colony of Ile Saint-Jean, now known as Prince Edward Island.

At this time the second wave of the Expulsion began from Ile Saint Jean and Cape Breton and continued in earnest in New Brunswick.

Weeks after the Expulsion began with the Bay of Fundy campaign (1755), the British forces raided villages at Chipoudy and Petitcodiac (Hillsborough, New Brunswick).

On September 10, 1757, Captain John Knox of the Forty-third Regiment was ordered to take part in an 800 man joint force of rangers and regular troops to march against Chipoudy, which seemed to be the originating point for the Acadian and Mi'kmaq raids on Chignecto.

[8] Almost seven months later, on March 28, 1758, Gorham's Rangers raided Chipoudy and found only women and children; the men had left for Fort Cumberland, where they attacked a schooner.

[9] In June 1758, Lieutenant Meech of Benoni Danks' Rangers along with fifty-five men advanced up the Petitcodiac River, suspecting that this was where the Acadian and Mi'kmaq raids originated.

They arrived at present day Moncton and Danks' Rangers ambushed about thirty Acadians, who were led by Joseph Broussard (Beausoleil).

Major General Amherst dispatched Brigadier James Wolfe to the northeast along the coast in the Gulf of St. Lawrence campaign (1758).

[15] After Wolfe had left the area, the 1760 Battle of Restigouche led to the capture of several hundred Acadians at Boishébert's refugee camp at Petit-Rochelle.