A spin-off series, titled Pet Shop of Horrors: Passage-hen, which follows Count D's grandfather in Fin de siècle Paris, was irregularly published in HarperCollins Japan's Mugentō (2013) and Harlequin Original (2015–2017); five volumes were released.

Another spin-off, titled Petshop of Horrors: Hyōhaku no Hakobune-hen, featuring Count D's father as the protagonist, was serialized in Harlequin Original from 2018 to 2020, with its chapters collected in three volumes.

As the series progresses, he learns more about the pet shop and D himself, entering into a strange friendship of sorts with D as he works to uncover the truth.

[6] Ohzora Publishing released ten tankōbon volumes, under the Missy Comics DX imprint, from March 1995 to September 1998.

[12] In August 2024, Seven Seas Entertainment announced that it had licensed the series and it will be released in a collector's edition with an all-new translation starting in February 2025.

[b] In June 2007, the company announced that it would cease operations,[20] and the magazine went on to be published by Asahi Shimbun Publications, until it last issue released on April 23, 2009,[21] and the series continued as a webcomic on Yahoo!

The anime first aired as a miniseries on the TBS television network (as part of their now-defunct programming block "Wonderful") before being sold on VHS and LaserDisc.

[40] Urban Vision released the Pet Shop of Horrors anime in North America, initially across two VHS tapes (each available in either subtitled or dubbed format) in February and May 2000 respectively.

Carlo Santos of Anime News Network described the plot of Pet Shop of Horrors: Tokyo as "the series' greatest strength but also its weakness: the plot formula makes it easy to dish out just the right amount of human drama, but those familiar with the Pet Shop will see each twist coming—and may even find some of them to be too far-fetched."

Santos also felt that the art was "not particularly horrifying," commenting that "it's clear that Akino struggles with any artwork beyond the usual range of attractive young men, fashionable women and the occasional bizarre creature."

Instead, the pleasure comes from Matsuri Akino's talent for truthful dialogue, attention to detail in the art, and a fine sense of how to portray both laughter and dread.