He came to the fore in the Turkish literature of the Republican era with his psychological works such as Dokuzuncu Hariciye Koğuşu (Ninth External Ward).

He created Cingöz Recai, a character inspired by Arsène Lupin of the French writer Maurice Leblanc.

His good relationships with Nâzım Hikmet and Necip Fazıl Kısakürek turned into pen fights over time.

[2] Peyami Safa was born on April 2, 1899, in Gedikpaşa and named after Tevfik Fikret, one of the poets of Servet-i Fünûn.

His father İsmail Safa was referred to as a "mother-born poet" by Muallim Naci and belonged to a family of Trabzon origin.

Peyami Safa's father was one of the opponents of Abdülhamid II and died in Sivas while in exile without leaving anything financial to his family.

[7] He developed the knowledge of French by memorizing Petit Larousse, a gift from his father's close friends, Abdullah Cevdet, and began to be interested in medicine, psychology and philosophy books besides literary works.

Yakup Kadri says, "You brought us a style," Yahya Kemal said, "Peyami is the most beautiful work of Ismail Safa".Peyami Safa, who left his teaching position at the Rehber-i İttihad School during the armistice period in 1918, started publishing the newspaper Twentieth Century (Yirminci Yüzyıl) with his brother.

When he received a degree in the story contest organized by Alemdar newspaper, he was encouraged to write by the leading writers of the period.

After Yirminci Yüzyıl was closed, they continued to work for other newspapers such as Tercüman-ı Hakikat and Tasvîr-i Efkâr (1922) after the declaration of the Republic.

His article titled "New Literary Circles" published in Hilal-i Ahmer magazine led to a pencil fight with Ahmet Haşim (1928).

[11] In the early years, under the influence of Abdullah Cevdet, he wrote articles in Ijtihad magazine with positivist and materialist thoughts.

When Nâzım Hikmet returned to Turkey benefiting from the amnesty law, Safa published a poem entitled "Volcano", written by Nazım for the forgiveness of him in Cumhuriyet.

Nâzım Hikmet, Sabahattin Ali, Vâlâ Nureddin and Cevat Şakir Kabaağaçlı were among the most well-known contributors of this magazine.

It would be sold by ten thousand, one hundred thousand, one million; if they knew how to read and write the self and pure masses of people who heard the anguish, torment and joy with great enthusiasm.Safa published an article entitled Varız Diyen Nesil (The Generation who says We Exist) in the first issue of the journal Hareket.

Safa was accused of being Bolshevik for participating in the discussions titled Putları Yıkıyoruz (We Are Destroying the Idols), which started in Resimli Ay, together with Nâzım Hikmet and writing articles in the left-wing newspaper Tan.

[citation needed] Nâzım Hikmet accused Peyami Safa in his article titled Coffee and Casino Intellectuals written in Tan under the pseudonym Orhan Selim.

Peyami Safa also responded to Nâzım Hikmet under the series titled Biraz Aydınlık in the magazine Hafta, which he published with his brother.

[citation needed] In the following process, Peyami Safa's works with the signature of Server Bedi and Cingöz Recai typing became the main subject of the discussions between the two.