The Pfeiffer Falcons are the athletic teams that represent Pfeiffer University, located in Misenheimer, North Carolina, in intercollegiate sports at the Division III level of the National Collegiate Athletic Association (NCAA).

The Falcons have primarily competed in the USA South Athletic Conference since the 2017–18 academic year.

In 2009, varsity student-cyclist Joey Rosskopf won the overall Division II national road cycling championships.

For the first time in Pfeiffer men's soccer history the Falcons are National Champions, finishing the season a perfect 25–0.

The Falcons become the first undefeated champion in Division II men's soccer since Southern Connecticut State posted a 20–0 mark in 1999.