As the Head of the COVID-19 National Steering Committee, he was dubbed the "Commander-in-chief" in Vietnam's response to the pandemic alongside Nguyễn Xuân Phúc.

[3] Thanks to the nationwide vaccination strategy, Vietnam reopened its economy and registered positive GDP growth for 2021 before breaking a record high rate in 2022.

[4] In foreign affairs, his government has established close relationships with many countries, including upgrades in diplomatic relations with Australia and the United States.

In March 1991, Phạm Minh Chính became an officer of the Ministry of Foreign Affairs, working at the Vietnamese Embassy in Romania.

However, the Vietnamese economy faced many difficulties, the need for funding for the purchase of vaccines is very large and the state budget is limited.

Facing that situation, Prime Minister Phạm Minh Chính signed and promulgated Resolution 53/NQ-CP approving the establishment of a COVID-19 vaccine fund on May 27, 2021.

The anti-epidemic experience continues to support and prioritize the provision of friendly forces to Ho Chi Minh City in an online meeting on the morning of 4 July 2021.

[18] Facing the epidemic situation with increasing numbers of infections and complicated developments in the Southern provinces, Prime Minister Pham Minh Chinh signed Official Dispatch No.

[19] On 31 July 2021, Chính issued a telegram requesting southern provinces/cities to continue social distancing for an additional 14 days from 12:00 am on 2 August 2021 when the epidemic situation becomes extremely complicated.

General Secretary Nguyễn Phú Trọng has reached a unanimous conclusion to assign Phạm Minh Chính as Head of the National Steering Committee for COVID-19 epidemic prevention.

HCM "must detect F0 early, reach out immediately for appropriate classification and treatment, including testing, prioritizing high-risk people on the morning of 25 August 2021.

[22] On 13 October 2021, Phạm Minh Chính attended and spoke at the 4th "Russian Energy Week" Forum in video recording.

[23] Phạm Minh Chính attended and delivered important speeches at the COP26 Conference, attended and spoke at events announcing the initiatives of a number of important partners on the sidelines of COP26 such as the announcement of the Global Methane Emission Reduction Commitment demand, action on forests and land use.

[25][26] On May 13 (local time), Prime Minister Pham Minh Chinh and Leaders of the Association of Southeast Asian Nations attended official working sessions of the Special ASEAN Summit.

Vietnam and France are determined to introduce cooperation frameworks between the two countries, from politics - diplomacy, security - defense to economics - trade - investment, science and technology, health, education - training.

[30] At the talks held on the morning of 1 May, both men expressed their joy at the outstanding development of Vietnam-Japan relations and reached a broad common understanding of the major direction and measures to continue working together.

[31] On May 12, 2023, Prime Minister Phạm Minh Chính had a meeting with US President Joe Biden at the White House.

[32] In September 2023, following the signing of the Vietnam-US Comprehensive Strategic Partnership, Prime Minister Chính began a visit to Brazil and the United States.