[3][4] Phanerochaete has traditionally been delimited based on the overall morphology of the fruit body, as well as microscopic characteristics including the nature of the hyphal structure, cystidia, and spores.

The hyphal system is monomitic, with simple-septate generative hyphae; single or multiple clamps may be present in the subiculum.

[5] Phanerochaete includes white rot fungi that are able to degrade the woody polymer lignin to carbon dioxide.

The genome of Phanerochaete chrysosporium was sequenced and shows the genetic potential to make over 100 cytochrome P450 monooxygenases.

[7] White rot fungi have been used in bioremediation efforts to break down potentially harmful chemicals in soil and in water.