Pharmacie du Cerf was established in 1268 in Strasbourg, Alsace.

[1] Dating to 1268, it stands at the corner of the Rue Mercière and the Place de la Cathédrale in the shadow of Strasbourg Cathedral.

A fire on 15 August 1268 resulted in the building being reconstructed, a process completed by 1300.

[2] Between 1268 and 1398, the pharmacy was run by the Philippi family: Heinrich, his son Hesso and his grandson Hesselin.

The property subsequently became a dwelling, and in 1432 it was occupied by Pope Pius II Aenas Sylvius Piccolomini.