[1] One characterized member of this family, pneumococcal EJ-1 phage holin (EJh; TC# 1.E.11.1.3), is a hydrophobic peptide of 85 amino acyl residues in length (aas) with 2 putative transmembrane segments (TMSs) displaying lethal inner membrane disruptive activity.
Oligomeric channels of various sizes form depending on the peptide to lipid ratio.
[3] A representative list of proteins belonging to the φ11 holin family can be found in the Transporter Classification Database.
As of 10 March 2016, this article is derived in whole or in part from Transporter Classification Database (TCDB).
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