Hendrie has also acted professionally on a number of occasions, notably in a recurring role on the drama The Unit, as well as the voice of multiple characters on the animated comedies F is for Family, Rick and Morty, Futurama, King of the Hill and The Midnight Gospel.

[6] Hendrie's family home was repossessed, forcing them to move into a small rented apartment where he slept on a couch during his senior year in high school.

[7] In late September 1990, Hendrie introduced his first fictional on-air character on his radio talk show: Iraqi Raj Fahneen.

An entire cast of characters evolved, and in 18 months Hendrie took the show to major market stations in Atlanta, Minneapolis, and Miami and eventually back to Los Angeles.

"[19] On Saturday, November 20, 2010, KFI in Los Angeles announced that Phil Hendrie and his cast of voices were joining the station's weekend lineup.

and the Chechen terrorist in Trey Parker's and Matt Stone's motion picture Team America: World Police and starred in Steven Levitan's animated TV pilot Phil Hendrie.

Also that year, Hendrie had parts in the TV movies Mike Birbiglia's Secret Public Journal and Giants of Radio.

[27][28] In 2014, Hendrie played a fictionalized version of himself in the TV series Maron, and narrated a segment of the Comedy Central program Drunk History on the show's episode featuring the story of the late Hawaii Senator Daniel Inouye.

In 2015, Hendrie joined F is for Family to play various background characters.,[29] and later year that made his debut on the Cartoon Network's Adult Swim series Your Pretty Face is Going to Hell as the voice of Cerberus.

In 2019, Hendrie rejoined the cast of Your Pretty Face is Going to Hell - created by Dave Willis and Casper Kelly - with the on-screen role of "Stan the Man".

Also in 2019, Hendrie was set to play the lead as an "insane" grandparent in the CBS’ multi-camera comedy, Our House, opposite of Katherine Heigl and Malcolm Barrett.

[30] Recorded in late 2019 and broadcast in 2020, Hendrie voiced the "Universe Simulator" and a variety of other characters on the Netflix animated series, The Midnight Gospel.

Other than Duncan Trussell, Co-Creator and star of The Midnight Gospel, Hendrie is the only other voice actor to appear in each episode of the debut season.

In 2020, Hendrie performed the voice of Albert Einstein in the hit CBS sitcom, Young Sheldon and cast as Police Captain Entenille in a 2024 horror comedy film Destroy All Neighbors.

"[32] In August that same year, Hendrie launched a podcast version of his national radio show on iTunes for his Backstage Pass subscribers.

[33] In 2012, Hendrie extended his brand to Pandora with a collection of comedy bits featuring such characters as Jay Santos, Chris Norton, Bobbie Dooley, David G. Hall and Ted Bell.

[35] Directed by Patrick Reynolds, Produced by Jordan Brady, and distributed by Freestyle Digital Media, "HENDRIE" is a feature documentary on the legendary talk-radio comic legend Phil Hendrie, "who influenced a legion of great comedic minds through his innovative and relatively short-lived, off-the-wall radio show.

The film chronicles the life of a radio personality that dared to satirize the very medium he was part of, using a distinct and original method that hasn't been attempted before or since."

Notable personalities interviewed on-camera include Bill Hader, Judd Apatow, Kevin Pollak, Gary Oldman, Henry Rollins, Dana Gould, Wayne Federman, David Hall, Jeff Baker, and many others.

These individuals have entertained, informed, and enriched listeners with their special talents, and it is an honor to recognize them as the Radio Hall of Fame Class of 2024.”[37]