He served in numerous European and Middle Eastern theaters, including an appointment as the deputy base chief for the field office in Istanbul in the late 1980s.

[4] In August 2005, Giraldi wrote an article for The American Conservative that outlined his supposed knowledge of a contingency plan under development by the George W. Bush administration involving a potential nuclear attack on Iran.

[9] In another article that same year, Giraldi revealed that the outing of CIA officer Valarie Plame was part of a larger U.S. conspiracy to cover-up the forgery of documents used to implicate Iraq in the attempted acquisition of nuclear material.

[12] Noah Pollak wrote in Commentary magazine in August 2008: "In Giraldi’s world, scratching the surface of almost any event exposes the sinister machinations of international Jewry".

[14] In 2004, in a privately circulated newsletter co-written with Vincent Cannistraro, a retired CIA counter-terrorism chief, Giraldi said Turkish sources had reported that Turkey was concerned by Israel's alleged encouragement of Kurdish ambitions to create an independent state and that Israeli intelligence operations in the area included anti-Syrian and anti-Iranian activity by Kurds.

[17] The Israeli embassy, the United States Department of Justice, and Giraldi all declined to comment for an article on the allegations in the biweekly New York Arab-community newspaper Aramica.

[18][19] In September 2017, Valerie Plame encountered much criticism on Twitter when she retweeted Giraldi's Unz Review column "America's Jews are Driving America's Wars", and then when it was reported she had retweeted previous columns by Giraldi making claims about Jewish influence in American foreign policy, including "Why I Dislike Israel" (2014).

He concluded: "The only alternative is for American citizens who are tired of having their country's national security interests hijacked by a group that is in thrall to a foreign government to become more assertive about what is happening.

[20] Alan Dershowitz wrote for The Jerusalem Post: "In other words, Jewish supporters of Israel, like [Bill] Kristol and me, should have to wear the modern day equivalent of a yellow star before we are allowed to appear on TV.

"[25] In a 2019 article for the Strategic Culture Foundation, Giraldi described the US as engaged in a deliberate campaign to start a war with Iran, based on a threat "falsified" and "contrived" by John Bolton in collaboration with Israeli leader Benjamin Netanyahu, as assertion described by analyst Mitchell Bard as "in the grand tradition of antisemitic conspiracy theories".

[28] He said in the same month in an article for the Strategic Culture Foundation (described by the American Jewish Committee (AJC) as an "extreme-right propaganda website with a Russian domain") that "If one even considers it possible that the United States had a hand in creating the coronavirus at what remains of its once extensive biological weapons research center in Ft Detrick Maryland, it is very likely that Israel was a partner in the project".