It connects from Main North Road adjacent to the Elizabeth City Centre to John Rice Avenue, and continues as a minor road ending at the Little Para River linear park.

Philip Highway commences at the intersection of Main North Road and Yorktown Road and heads in a southerly direction through the commercial centre of Elizabeth, with the main Elizabeth City Centre on one side and other shops and businesses opposite.

Once it crosses Hogarth Road, it enters the industrial part of Elizabeth South passing a number of factories, the largest of which is the Holden factory.

Philip Highway ends as an arterial road immediate after Holden at the roundabout with John Rice Avenue, and continues as a minor road for another 500 metres (0.3 mi) through residential Elizabeth Vale to terminate at the South Para River reserve at the intersection with Prunus Avenue.

Philip Highway is entirely contained within the City of Playford local government area.