Pho Chai (Thai: โพธิ์ชัย, pronounced [pʰōː tɕʰāj]; Northeastern Thai: โพธิ์ไซย,[citation needed] pronounced [pʰo᷇ː sa᷇j]) is a district (amphoe) in the northern part of Roi Et province, Thailand.

Neighboring districts are (from the east clockwise): Phon Thong, Selaphum, Chiang Khwan of Roi Et Province; Rong Kham, Don Chan, and Kuchinarai of Kalasin province.

The minor district (king amphoe) was created on 1 April 1974, when the four tambons, Chiang Mai, Kham Pia, Sa-at, and Kham Pha-ung, were split off from Phon Thong district.

[2] The district is divided into nine sub-districts (tambons), which are further subdivided into 112 villages (mubans).

Chai Wari covers parts of tambon Kham Pia, and Chiang Mai covers tambon Chiang Mai.