The old city was at Wat Amphawan, Tambon Phrom Buri.
Later the center of the city was moved to Pak Bang Muen Han (ปากบางหมื่นหาญ) and to the north side of Wat Phromma Thephawat.
In 1943 the district office was moved to its present location on the north side of Wat Kudi Thong.
Neighboring districts are (from the east clockwise) Tha Wung of Lopburi province, Chaiyo and Pho Thong of Ang Thong province, Tha Chang and Mueang Sing Buri of Sing Buri Province.
Phrom Buri is divided into seven sub-districts (tambons), which are further subdivided into 42 administrative villages (mubans).