[1][2] Common name Guinea river frog has been coined for it,[2][3] although it is actually associated with drier parts of primary rainforest.

[4] Phrynobatrachus guineensis occur in the drier parts of primary rainforest at elevations up to 1,000 m (3,300 ft) above sea level.

[1] Breeding takes place in tree holes, but also in tiny waterbodies such as empty nuts and snail shells.

It is negatively impacted by habitat loss caused by agricultural development, logging, and expanding human settlements.

It occurs in Taï National Park and Mount Nimba World Heritage Site.