Phu Khiao (Thai: ภูเขียว, pronounced [pʰūː kʰǐaw], Northeastern Thai: ภูเขียว; pronounced [pʰu᷇ː kʰǐaw]) is a district (amphoe) in the northern part of Chaiyaphum province, northeastern Thailand.

Phu Khiao was a city (mueang) in the early years of the Rattanakosin Kingdom era at the end of the 18th century.

The center of the city was in Ban Mueang Kao (which now is in Kaset Sombun district).

During the Thesaphiban administrative reforms Mueang Phu Khiao was downgraded to be a district of Chaiyaphum province in 1899.

It was later renamed Phak Pang after the central tambon, and changed back to Phu Khiao in 1939.