Macrosaccus uhlerella is a moth of the family Gracillariidae.

It is known from Illinois, Missouri, New York, Colorado and Texas in the United States.

The mature mine is an elongate-oval, whitish blotch located on the underside of the leaf usually near the edge of the leaflet.

Eventually, as the mine becomes tentiform, the leaf edge is slightly curled.

This article relating to moths in the subfamily Lithocolletinae is a stub.