Picola was close to the coach route from Echuca to Tocumwal and had a general store, a Union Church and a primary school which was established in 1879.

However, Picola fell behind, likely due to its lack of a substantial watercourse compared to Nathalia's position on the Broken Creek.

[6] It was used to transport wheat, livestock and red gum from the Barmah National Park.

It has been burnt down and rebuilt twice: on 19 August 1936, leading the wooden building to be replaced by a brick structure, and on 12 April 1939.

Painted by Jimmy Dvate, it features flora and fauna from the Barmah National Park.