Piero Luigi Vigna (1 August 1933 - 28 September 2012) was an Italian magistrate.
He was initially pretore in Florence and Milan, returning to his native city's prosecution office in 1965.
In 1991 he became Chief Prosecutor: his investigations included those on right-wing terrorism, the Train 904 bombing and the so-called Monster of Florence, as well as on the presence of mafia in Tuscany.
On 14 January 1997, Vigna was appointed National Antimafia Prosecutor, a position he held until reaching retirement age in 2005.
Until his death he remained honorary president of Magistratura Indipendente, a magistrates' association.