Son of the senator Ludovico Barozzi, he began to study Latin and Greek letters with his companions Pietro Delfino and Leonardo Loredan, all pupils of the master Pierleone Leoni.

[1] [2] [3] He devoted particular attention to architectural studies, which he put into practice in rearranging and decorating public and ecclesiastical structures, influenced by the style of Alberti.

[3] It is in Padua in the Museo Diocesano, the former bishop's palace, which Barozzi transformed into a magnificent Renaissance showplace.

[5] In recent times he is considered influential in humanism, and Hubert Jedin describes him as an exemplary bishop.

The erudite bishop Pietro Barozzi left a large collection of books: juridical, theological works, of Greek, Latin and vernacular classics and humanist authors.