He was born Pietro Giuffrida, in Mascalucia Province, Catania, Sicily, to a farming family in 1885 and began to play the chromatic button accordion at the age of six.

In 1889, he joined the Municipal Conservatory of Fine Arts, originally taking up the cornet, and became a pupil of Francesco Paolo Frontina (whom he took his professional stage name from, as a tribute) studying composition and harmony.

He briefly served as a cornettist with a British Army Band in Malta, but after health complications after contracting malaria, he went back to his first love of the accordion.

In 1905, Frosini emigrated to San Francisco and whilst performing Poet and Peasants Overture, by Suppe, was discovered by a talent agent of the Orpheum Vaudeville Circuit.

He traveled extensively on the vaudeville circuit in America and abroad and on a tour of England playing in music halls and provinces even performed for the King George V and releasing several records under his own name and pseudonyms, S. Frigoli and G. Arditti.