But the position of professor of Medicine was granted to Jacopo Zanettini, and by 1378, Pietro had moved to teach at the University of Bologna.
He moved to Ferrara, then Pavia, where he became the personal physician of Gian Galeazzo Visconti and taught at the university.
In 1398, as part of a medical manuscript printed in Venice, he published a series of recommendation for the care of those afflicted by bubonic plague (Consilium pro peste evitanda).
He advanced the notion that the disease was contagious and recommended isolation of the ill, fumigation of their rooms, masking by those coming in contact, and certain diets for the afflicted.
Pietro appears to have been able to travel far afield, perhaps to Spain and Germany, to treat Henry III of Castile and Rupert of the Palatinate respectively.