Caruso was born in Palermo, Sicily and debuted as a dramatic stage actor in his home town in 1957.

In 1965 he moved to Rome and entered the theatre company "Il Bagaglino".

He gained great popularity taking part in several RAI variety shows such as Che domenica amici (1968), Gli amici della domenica (1970), Teatro 10 (1971),Dove sta Zazà (1973), Mazzabubù (1975), Due come noi (1979).

[2] In 2001, the Extraordinary Commissioner of the city Ettore Serio called Caruso to repeat the experience.

He was married to stage actress Marilisa Ferzetti and was the father of the voice actor Francesco Caruso.