[2][4] Despite its initial promise and relatively mild stimulant effects compared to stronger alternatives, concerns about its abuse potential led to its regulation and withdrawal from widespread use in many countries during the late 1970s.

[2] Pipradrol is now classified as a controlled substance in several nations, including the United Kingdom, where it is typically placed in less restrictive drug schedules due to its lower abuse potential compared to other stimulants.

Rarer side effects include dry mouth, tremor, hypertension, euphoria, depression, and very rarely psychosis or convulsions.

[2] Its mechanism of action involves blocking the reuptake of these neurotransmitters, leading to increased levels in the synaptic cleft and prolonged stimulation of postsynaptic neurons.

[2] Unlike amphetamines, pipradrol exhibits a more intense action on higher brain centers without significantly affecting blood pressure or respiration.