Download coordinates as: Piscasaw Creek is a 31.6-mile-long (50.9 km)[1] tributary of the Kishwaukee River in the U.S. states of Wisconsin and Illinois.

[4] Piscasaw Creek is classified as a "Class A" drainage by the criteria established by the Illinois Environmental Protection Agency, signifying the small river's relative health with respect to waterborne nutrients and chemicals.

[3] In 2008 the Illinois Natural History Survey examined Piscasaw Creek at two different sites in McHenry County's Beck's Woods.

[7] The rainbow trout in Piscasaw Creek are stocked each year by the Illinois Department of Natural Resources and the McHenry County Conservation District.

Both species are known to breed successfully, though the overwhelming populations of various chub and sucker often deter most fisherman from consistently fishing it.

The mussels Ellipto dilatata (Spike) and Alasmidonta viridis (Slippershell) have been documented in the creek; the former is threatened, the latter endangered.