It is about 5 miles (8 km) north of Henley-on-Thames, in the Stonor valley in the Chiltern Hills about 430 feet (130 m) above sea level.

[3] One of the stained glass windows was made in 1967 by John Piper[3] and Patrick Reyntiens.

[4] Southwest of the parish church is an 18th-century barn that seems to include the remains of an early 14th-century chapel.

With the support of the Stonors and Jesuit priests who stayed with them, a number of Pishill families remained Roman Catholic throughout the 16th, 17th and 18th centuries.

In 1878 the Church of England incumbent of Pishill reported that a third of the 200 population of his parish were Roman Catholic.