As a Mac-only app, Pixelmator Pro relies heavily on technologies from Apple platforms such as Metal, CoreML, Core Image, AVFoundation, GCD, and SwiftUI.

[4] Pixelmator Pro was generally well-received by reviewers who praised its deep use of machine learning,[7] fully macOS-native design,[8] and relatively affordable one-time purchase compared to subscription software such as Adobe Photoshop.

[9][10] It was awarded Apple's Mac App of the Year in 2018.

[11] On November 1, 2024, the Pixelmator Team announced that they were to be acquired by Apple, subject to regulatory approval.

[12] Their site promises "There will be no material changes to the Pixelmator Pro, Pixelmator for iOS, and Photomator apps at this time."