A placental site nodule (PSN) is benign remnant from a previous pregnancy.

PSNs are diagnosed by examining the tissue under a microscope, usually obtained with a dilation and curettage.

Typically, they consist of pink (hyaline) material using the standard stain and contain few cells.

Bizarre multinucleated cells may be present; however, there is no mitotic activity.

The differential diagnosis includes (cervical) squamous cell carcinoma, gestational trophoblastic disease, and exaggerated placental site.