Plai Phraya (Thai: ปลายพระยา, pronounced [plāːj pʰrā.jāː]) is a district (amphoe) in Krabi province, Thailand.

Neighboring districts are (from the north clockwise): Phanom, Phrasaeng, Chai Buri (all Surat Thani province); Khao Phanom and Ao Luek of Krabi Province; and Thap Put of Phang Nga province.

Khlong Phraya Wildlife Sanctuary is on the Surat Thani Province border.

The minor district (king amphoe) Plai Phraya was created on 15 June 1973, when the three tambons, Plai Phraya, Khao Khen, and Khao To, were split off from Ao Luek district.

[2] The district is divided into four sub-districts (tambons), which are further subdivided into 33 villages (mubans).