[3] It was also deliberately introduced into two Pacific islands in an attempt to control an invasion of the giant African land snail.

[4] However, P. manokwari does not live in urban coastal areas, perhaps due to environmental factors, such as lack of vegetation.

[4] P. manokwari mainly preys on small land snails, but it has been known to feed on various soil invertebrates, such as earthworms, slugs, and arthropods.

[7] Platydemus manokwari is the main predator of land mollusks, and preys upon the snails during most of their life cycle including young hatchlings.

[10] A rare observation of Platydemus manokwari scavenging on a dead human body was reported in 2024 in Australia.

P. manokwari is presumed to act as a transmission vector of the parasite to humans and affects the epidemiology of angiostrongyliasis.

It is possible that Platydemus manokwari is a vector because it has been occasionally found underside cabbage leaves which would be eaten raw as fresh salad.

These islands often harbor endemic radiations of rare and endangered snail species, which are a primary source of nutrition for Platydemus manokwari.

[3] The complete mitochondrial genome, 19,959-bp in length, was obtained in 2020; it contains 36 genes and is almost colinear with the mitogenomes of the two other species previously sampled from the Geoplanidae, Bipalium kewense and Obama nungara; however, the mitogenome of Platydemus manokwari has an unusually large Cytochrome c oxidase subunit II gene.