Pleasant Avenue is a north-south street in the East Harlem neighborhood of the New York City borough of Manhattan.

The neighborhood shrunk over the years, especially since the 1990s, and the smaller remaining Italian population mostly resides on Pleasant Avenue.

[4] Both in real life and in film, Pleasant Avenue has long been associated with the Mafia.

[5] The street was the headquarters of Anthony Salerno, head of the Genovese crime family, prior to his incarceration for racketeering in 1986.

[6] The Manhattan Center for Science and Mathematics, formerly Benjamin Franklin High School, is located on Pleasant Avenue.