Pliometanastes is an extinct genus of ground sloths of the family Megalonychidae endemic to North America during the Late Miocene epoch through very early Pliocene epoch (Hemphillian in the NALMA classification).

Its fossils have been found in Costa Rica and across the southern United States from California to Florida.

[1] Pliometanastes and Thinobadistes were the first of the giant sloths to appear in North America, the former around 9 million years ago.

[2] Both were in North America before the Panamanian Land Bridge formed around 2.7 million years ago, which led to the main pulse of the Great American Interchange.

It is then reasonable to presume that the ancestors of Pliometanastes island-hopped across the Central American Seaway from South America, where ground sloths arose.