[2] Tamano-Shata was born in Wuzaba, a village located near the city of Gondar in the Amhara Region of northern Ethiopia.

[1] She, her four siblings, and her father Menashe were among almost 7,000 Ethiopian Jews airlifted out of the country by Mossad to Israel between November 1984 and January 1985.

On 9 February 2018, she returned to the Knesset as a replacement for Ya'akov Peri,[9] who had resigned following allegations that he had leaked information during a corruption investigation twenty years beforehand.

[10] Prior to the April 2019 elections, Yesh Atid became part of the Blue and White, with Tamano-Shata placed 24th on the alliance's list.

[12][13] After being re-appointed to her ministerial role following the 2021 elections, she resigned from the Knesset under the Norwegian Law and was replaced by Alon Tal.