Pollienus Auspex was a member of the possibly Italian gens Pollieni.
Reaching the office of suffect consul sometime between AD 170 and 174, he was appointed Legatus Augusti pro praetore or governor of Dalmatia between 173 and 175.
He was next made Iudex ex delegatione Caesarum (or the judicial deputy of the emperor in Rome) between 176 and 180, when Marcus Aurelius and Commodus were on the Danube fighting the second of the Marcomannic Wars.
Pollienus Auspex was a man who wielded enormous influence in the imperial court.
In around AD 206 he successfully interceded before the emperor on behalf of his nephew Pollienus Sebennus who was accused of acting improperly while governor of Noricum, and even mocked the incoming emperor Septimius Severus when Severus announced his self-adoption into the imperial family of Marcus Aurelius.