Polystira florencae is a species of sea snail, a marine gastropod mollusk in the family Turridae, the turrids.

It is, pale brown, excepting the large median keel between summit and suture and a broad area that extends over a little more than half of the posterior part of the columella, which are white.

These are followed by about one half of a turn that is crossed by about 10 slightly retractively curved, axial ribs, which are about one fourth as wide as the spaces that separate them.

The postnuclear whorls are marked by very strong spiral keels, of which the most conspicuous one is the second one below the summit, which bears the deeply narrow posterior sinus.

[2] P. florencae can be found in Caribbean waters, ranging from the Bahamas south to Brazil.