They repeated as champions in 1954, but the 1953 championship did not finish when players from Ponce and San German were involved in a brawl which BSN officials could not control.

With the acquisition of Eddie Casiano and Bobby Joe Hatton in 2001, the team started re-building around them, with remaining key veteran players like Toñito Colón.

By the end of the 2013 season, the Lions reached the finals against the Quebradillas Pirates but after a six-game series they failed to win a championship trophy.

The Lions made their back-to-back title after six games and tied the BSN record, along with the Bayamón Cowboys and the San Germán Athletics, for most overall championships.

[7][8] The team recovered by defeating Club Atlético Lanús, runner-up of the Liga Nacional de Básquet, with scores of 90-73 on their second game.

[12] Leones de Ponce made its return to the FIBA Americas League in the 2017 edition as a measure to develop team chemistry prior to the BSN season,[13] hosting the opening round of Group D at Auditorio Juan Pachín Vicéns.

Prior to the final game of the group phase the team lost its regular SG Víctor Liz due to a calf injury,[20][21] going on to lose against Weber Bahía Blanca in overtime, 92-96.

[22] The home team games during the group phase averaged an assistance of 5,000 fans, which satisfied FIBA and led to a request to organize the following round.

[26] Despite resting regular SF Ángel Daniel Vassallo most of the game due to a knee injury, Ponce defeated San Lorenzo de Almagro with scores of 115-107 (following two overtimes) in the semifinal closer to advance to the final four.

[28][29] The team held an exhibition against the Cariduros de Fajardo, before leaving to fulfill the practice sessions scheduled upon their arrival to the South American country.

[33] Ponce finished this edition in the third place of the grand final, losing to eventual champion and home team Guaros de Lara (87-100) in the pivotal match before rebounding to win the consolation game over Mexico's Fuerza Regia (90-68).

[36] After an sponsor supported them, the Leones choose to participate in the 2018 FIBA Americas League despite having limited facilities (due to the passing of hurricane Maria in September 2017) and several roster losses that forced them to rely on nostalgia and bring former members for the tournament.

[37] Mike Rosario, Chris Gastón and Miguel Alí Berdiel headlined this makeshift group, which lost Arroyo, Filiberto Rivera and Liz from the previous edition.

[39] Playing abroad at Argentina, Ponce lost to local teams Estudiantes Concordia (66-81) and Regatas Corrientes (76-90), while defeating Hebraica Macabi of Uruguay (86-69).

[42][43][44] Efejuku was initially only brought back for the tournament, but later joined the roster as a regular after being nativized (following four years of continued residence) and acquired by Ponce in the 2019 BSN Draft.